Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Mahajan, Anubha; Taliun, Daniel; Thurner, Matthias; Robertson, Neil R.; Torres, Jason M.; Rayner, N. William; Payne, Anthony J.; Steinthorsdottir, Valgerdur; Scott, Robert A.; Grarup, Niels; Cook, James P.; Schmidt, Ellen M.; Wuttke, Matthias; Sarnowski, Chloé; Mägi, Reedik; Nano, Jana; Gieger, Christian; Trompet, Stella; Lecoeur, Cécile; Preuss, Michael H.; Prins, Bram Peter; Guo, Xiuqing; Bielak, Lawrence F.; Below, Jennifer E.; Bowden, Donald W.; Chambers, John Campbell; Kim, Young Jin; Ng, Maggie C. Y.; Petty, Lauren E.; Sim, Xueling; Zhang, Weihua; Bennett, Amanda J.; Bork-Jensen, Jette; Brummett, Chad M.; Canouil, Mickaël; Ec kardt, Kai-Uwe; Fischer, Krista; Kardia, Sharon L. R.; Kronenberg, Florian; Läll, Kristi; Liu, Ching-Ti; Locke, Adam E.; Luan, Jian’an; Ntalla, Ioanna; Nylander, Vibe; Schönherr, Sebastian; Schurmann, Claudia; Yengo, Loïc; Bottinger, Erwin P.; Brandslund, Ivan; Christensen, Cramer; Dedoussis, George; Florez, Jose C.; Ford, Ian; Franco, Oscar H.; Frayling, Timothy M.; Giedraitis, Vilmantas; Hackinger, Sophie; Hattersley, Andrew T.; Herder, Christian; Ikram, M. Arfan; Ingelsson, Martin; Jørgensen, Marit E.; Jørgensen, Torben; Kriebel, Jennifer; Kuusisto, Johanna; Ligthart, Symen; Lindgren, Cecilia M.; Linneberg, Allan; Lyssenko, Valeriya; Mamakou, Vasiliki; Meitinger, Thomas; Mohlke, Karen L.; Morris, Andrew D.; Nadkarni, Girish; Pankow, James S.; Peters, Annette; Sattar, Naveed; Stančáková, Alena; Strauch, Konstantin; Taylor, Kent D.; Thorand, Barbara; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tuomilehto, Jaakko; Witte, Daniel R.; Dupuis, Josée; Peyser, Patricia A.; Zeggini, Eleftheria; Loos, Ruth J. F.; Froguel, Philippe; Ingelsson, Erik; Lind, Lars; Groop, Leif; Laakso, Markku; Collins, Francis S.; Jukema, J. Wouter; Palmer, Colin N. A.; Grallert, Harald; Metspalu, Andres; Dehghan, Abbas; Köttgen, Anna; Abecasis, Goncalo R.; Meigs, James B.; Rotter, Jerome I.; Marchini, Jonathan; Pedersen, Oluf; Hansen, Torben; Langenberg, Claudia; Wareham, Nicholas J.; Stefansson, Kari; Gloyn, Anna L.; Morris, Andrew P.; Boehnke, Michael; McCarthy, Mark I.

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Anubha Mahajan
Mahajan et al., 2018

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Nature Research, Nature Genetics, 11(50), p. 1505-1513, 2018

DOI: 10.1038/s41588-018-0241-6

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@article{Mahajan2018,
  author = {Mahajan, Anubha and Taliun, Daniel and Thurner, Matthias and Robertson, Neil R. and Torres, Jason M. and Rayner, N. William and Payne, Anthony J. and Steinthorsdottir, Valgerdur and Scott, Robert A. and Grarup, Niels and Cook, James P. and Schmidt, Ellen M. and Wuttke, Matthias and Sarnowski, Chloé and Mägi, Reedik and Nano, Jana and Gieger, Christian and Trompet, Stella and Lecoeur, Cécile and Preuss, Michael H. and Prins, Bram Peter and Guo, Xiuqing and Bielak, Lawrence F. and Below, Jennifer E. and Bowden, Donald W. and Chambers, John Campbell and Kim, Young Jin and Ng, Maggie C. Y. and Petty, Lauren E. and Sim, Xueling and Zhang, Weihua and Bennett, Amanda J. and Bork-Jensen, Jette and Brummett, Chad M. and Canouil, Mickaël and Ec kardt, Kai-Uwe and Fischer, Krista and Kardia, Sharon L. R. and Kronenberg, Florian and Läll, Kristi and Liu, Ching-Ti and Locke, Adam E. and Luan, Jian’an and Ntalla, Ioanna and Nylander, Vibe and Schönherr, Sebastian and Schurmann, Claudia and Yengo, Loïc and Bottinger, Erwin P. and Brandslund, Ivan and Christensen, Cramer and Dedoussis, George and Florez, Jose C. and Ford, Ian and Franco, Oscar H. and Frayling, Timothy M. and Giedraitis, Vilmantas and Hackinger, Sophie and Hattersley, Andrew T. and Herder, Christian and Ikram, M. Arfan and Ingelsson, Martin and Jørgensen, Marit E. and Jørgensen, Torben and Kriebel, Jennifer and Kuusisto, Johanna and Ligthart, Symen and Lindgren, Cecilia M. and Linneberg, Allan and Lyssenko, Valeriya and Mamakou, Vasiliki and Meitinger, Thomas and Mohlke, Karen L. and Morris, Andrew D. and Nadkarni, Girish and Pankow, James S. and Peters, Annette and Sattar, Naveed and Stančáková, Alena and Strauch, Konstantin and Taylor, Kent D. and Thorand, Barbara and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Tuomilehto, Jaakko and Witte, Daniel R. and Dupuis, Josée and Peyser, Patricia A. and Zeggini, Eleftheria and Loos, Ruth J. F. and Froguel, Philippe and Ingelsson, Erik and Lind, Lars and Groop, Leif and Laakso, Markku and Collins, Francis S. and Jukema, J. Wouter and Palmer, Colin N. A. and Grallert, Harald and Metspalu, Andres and Dehghan, Abbas and Köttgen, Anna and Abecasis, Goncalo R. and Meigs, James B. and Rotter, Jerome I. and Marchini, Jonathan and Pedersen, Oluf and Hansen, Torben and Langenberg, Claudia and Wareham, Nicholas J. and Stefansson, Kari and Gloyn, Anna L. and Morris, Andrew P. and Boehnke, Michael and McCarthy, Mark I.},
  doi = {10.1038/s41588-018-0241-6},
  journal = {Nature Genetics},
  month = {oct},
  pages = {1505-1513},
  title = {Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps},
  url = {http://www.nature.com/articles/s41588-018-0241-6.pdf},
  volume = {50},
  year = {2018}
}

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