Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Pardiñas, Antonio F.; Wray, Naomi R.; Sklar, Pamela; Stahl, Eli A.; Won, Hyejung; Sims, R.; Sigurdsson, Engilbert; Silagadze, Teimuraz; Stefansson, Kari; Thomas, C.; Taylor, S.; Stefansson, Hreinn; Steinberg, Stacy; Tosato, Sarah; Werge, Thomas; Todd, S.; Williams, J.; Sørensen, H. J.; Spencer, B.; Støvring, H.; Strohmaier, J.; Sullivan, P.; Vassos, E.; Verbelen, M.; Walters, James T. R.; Pocklington, Andrew J.; Legge, Sophie E.; Hamshere, Marian L.; Af, Pardiñas; Holmans, Peter; Mantripragada, Kiran; Rees, Elliott; MacCabe, James H.; McCarroll, Steven A.; Baune, Bernhard T.; Breen, Gerome; Byrne, Enda M.; Dannlowski, Udo; Eley, Thalia C.; Hayward, Caroline; Escott-Price, Valentina; Martin, Nicholas G.; McIntosh, Andrew M.; Plomin, Robert; Porteous, David J.; Caballero, Armando; Ripke, Stephan; Geschwind, Daniel H.; Huckins, Laura M.; Ruderfer, Douglas M.; Aj, Pocklington; Santiago, Enrique; Carrera, Noa; Agerbo, Esben; Als, Thomas D.; Andreassen, Ole A.; Bækvad-Hansen, Marie; Mortensen, Preben Bo; Børglum, Anders D.; Pedersen, M. G.; Bybjerg-Grauholm, Jonas; Djurovic, Srdjan; Durmishi, Naser; Bishop, Sophie; Golimbet, Vera; Grove, Jakob; Hougaard, David M.; Mattheisen, Manuel; Molden, Espen; Harold, D.; Cameron, Darren; Mors, Ole; Nordentoft, Merete; Gerrish, A.; Chapman, J.; Pejovic-Milovancevic, Milica; Pedersen, Carsten Bøcker-Ø.; Abraham, R.; Hollingworth, P.; Pahwa, J.; Han, Jun; Hansen, Christine Søholm-Ø.; Denning, N.; Hubbard, Leon; Powell, J.; Proitsi, P.; Lupton, M.; Se, Legge; Lovestone, S.; Lynham, Amy; Passmore, P.; Craig, D.; McGuinness, B.; Johnston, J.; Maier, W.; Jessen, F.; Heun, R.; Schurmann, B.; Ramirez, A.; Becker, T.; Herold, C.; Lacour, A.; Drichel, D.; Nothen, M.; Goate, A.; Cruchaga, C.; Nowotny, P.; Morris, J. C.; Mayo, K.; O'Donovan, M.; Pedersen, Marianne Giørtz; Achilla, E.; Barr, C. L.; Böttger, T. W.; Cohen, D.; Curran, S.; Dempster, E.; Dima, D.; Ml, Hamshere; Sabes-Figuera, R.; Pedersen, C. B.-Ø.; Flanagan, R. J.; Frangou, S.; Owen, M. J.; Frank, J.; Gasse, C.; Gaughran, F.; Giegling, I.; Hannon, E.; Hartmann, A. M.; Heißerer, B.; Helthuis, M.; Horsdal, H. T.; Ingimarsson, O.; Jollie, K.; Kennedy, J. L.; Köhler, O.; Konte, B.; Lang, M.; Lewis, C.; MacCaba, J.; Malhotra, A. K.; McCrone, P.; Meier, S. M.; Mill, J.; Nöthen, M. M.; Rietschel, M.; Rujescu, Dan; Schwalber, A.; Owen, Michael J.; Collier, David A.; Kirov, George; O’Donovan, Michael C.; O'Donovan, M. C.; Crestar, Consortium

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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Journal article published in 2018 by Antonio F. Pardiñas

, Naomi R. Wray, Pamela Sklar, Eli A. Stahl, Hyejung Won, R. Sims, Engilbert Sigurdsson, Teimuraz Silagadze, Kari Stefansson, C. Thomas, S. Taylor, Hreinn Stefansson, Stacy Steinberg, Sarah Tosato, Thomas Werge and other authors.

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