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Cell Press, Trends in Molecular Medicine, 10(20), p. 541-543, 2014

DOI: 10.1016/j.molmed.2014.07.002

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Advances in epigenome-wide association studies for common diseases

Journal article published in 2014 by Dirk S. Paul ORCID, Stephan Beck
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Epigenome-wide association studies (EWASs) provide a systematic approach to uncovering epigenetic variants underlying common diseases. Discoveries have shed light on novel molecular mechanisms of disease and enabled the application of epigenetic variants as biomarkers. Here, we highlight the recent advances in this emerging line of research and discuss key challenges for current and future studies.