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American Society of Hematology, Blood, 2(131), p. 202-214

DOI: 10.1182/blood-2017-06-790204

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Decitabine enhances targeting of AML cells by CD34+ progenitor-derived NK cells in NOD/SCID/IL2Rgnull mice

Distributing this paper is prohibited by the publisher
Distributing this paper is prohibited by the publisher

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Abstract

Key Points CD34+ progenitor-derived NK cells and HMAs potently cooperate against AML cells. DAC-mediated modulation of CD34-derived NK cell phenotype, function, and trafficking results in enhanced anti-leukemic effect in vivo.