Published in
American Association for the Advancement of Science, Science Translational Medicine, 423(10), 2018
DOI: 10.1126/scitranslmed.aai7795
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Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease
Journal article published in 2018 by
Ken Y. Hui,
Heriberto Fernandez-Hernandez,
Jianzhong Hu,
Adam Schaffner 
,
Nathan Pankratz ,
Nai-Yun Hsu ,
Ling-Shiang Chuang ,
Shai Carmi ,
Nicole Villaverde ,
Xianting Li ,
Manual Rivas ,
Adam P. Levine ,
Xiuliang Bao ,
Philippe R. Labrias ,
Talin Haritunians
and other authors.
,
Nathan Pankratz ,
Nai-Yun Hsu ,
Ling-Shiang Chuang ,
Shai Carmi ,
Nicole Villaverde ,
Xianting Li ,
Manual Rivas ,
Adam P. Levine ,
Xiuliang Bao ,
Philippe R. Labrias ,
Talin Haritunians
and other authors.
This paper is available in a repository.
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Abstract
Crohn’s disease (CD)–associated variants in the LRRK2 gene for risk (N2081D) and for protection (N551K) mediate shared effects in CD and Parkinson’s disease.