Published in
American Society of Hematology, Blood, 23(130), p. 2504-2515, 2017
DOI: 10.1182/blood-2017-03-771576
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A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice
Journal article published in 2017 by
Reema Jain,
Julie M. Sheridan,
Antonia Policheni,
Melanie Heinlein,
Luke C. Gandolfo,
Grant Dewson,
Gordon K. Smyth,
Stephen N. Sansom,
Nai Yang Fu,
Jane E. Visvader,
Georg A. Holländer,
Andreas Strasser,
Daniel H. D. Gray 
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Abstract
Key PointsMCL-1 is essential, but BCL-2 and BCL-XL are dispensable, for TEC survival and thymic function. Epidermal growth factor upregulates MCL-1 in TECs.