Published in
Oxford University Press (OUP), Bioinformatics, 4(31), p. 555-562
DOI: 10.1093/bioinformatics/btu686
Links
- ORCID
- ORCID
- Oxford University Press (OUP) | PDF
- [lup.lub.lu.se] | PDF
- [portal.research.lu.se] | PDF
- [lup.lub.lu.se] | PDF
Tools
DIANA - algorithmic improvements for analysis of data-independent acquisition MS data.
,
George Rosenberger ,
Uwe Schmitt,
Lars Malmström,
Johan Malmström,
Fredrik Levander
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Abstract
Data independent acquisition mass spectrometry has emerged as a reproducible and sensitive alternative in quantitative proteomics, where parsing the highly complex tandem mass spectra requires dedicated algorithms. Recently, targeted data extraction was proposed as a novel analysis strategy for this type of data, but it is important to further develop these concepts to provide quality-controlled, interference-adjusted and sensitive peptide quantification.