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American Association for the Advancement of Science, Science, 5985(328), p. 1529-1529, 2010

DOI: 10.1126/science.1189132

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Reassortment of pandemic H1N1/2009 influenza A virus in swine

Journal article published in 2010 by D. Vijaykrishna, L. L. M. Poon ORCID, H. C. Zhu, S. K. Ma, O. T. W. Li, C. L. Cheung, G. J. D. Smith ORCID, J. S. M. Peiris, Y. Guan
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This paper is available in a repository.

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Abstract

The emergence of pandemic H1N1/2009 influenza demonstrated that pandemic viruses could be generated in swine. Subsequent re-introduction of H1N1/2009 to swine has occurred in multiple countries. Through systematic surveillance of influenza viruses in swine from a Hong Kong abattoir, we characterize a reassortant progeny of H1N1/2009 with swine viruses. Continued reassortment of H1N1/2009 with swine influenza viruses could produce variants with transmissibility and altered virulence for humans. Global systematic surveillance of influenza viruses in swine is warranted.