Published in
Royal Society of Chemistry, RSC Advances, 49(6), p. 42794-42806, 2016
DOI: 10.1039/c6ra04957e
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Synthesis and biological evaluation of novel analogues of batracylin with synthetic amino acids and adenosine: an unexpected effect on centromere segregation in tumor cells through a dual inhibition of topoisomerase IIα and Aurora B
Journal article published in 2016 by
Wioleta Januchta,
Marcin Serocki,
Krystyna Dzierzbicka 
,
Grzegorz Cholewinski ,
Monika Gensicka,
Andrzej Skladanowski
,
Grzegorz Cholewinski ,
Monika Gensicka,
Andrzej Skladanowski
This paper is made freely available by the publisher.
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Abstract
In the search for new anticancer agents we designed and synthesized batracylin derivatives with linking synthetic amino acid side chains of different lengths and adenosine.