@article{Moreno2021, abstract = {Abstract The EMBL-EBI Expression Atlas is an added value knowledge base that enables researchers to answer the question of where (tissue, organism part, developmental stage, cell type) and under which conditions (disease, treatment, gender, etc) a gene or protein of interest is expressed. Expression Atlas brings together data from >4500 expression studies from >65 different species, across different conditions and tissues. It makes these data freely available in an easy to visualise form, after expert curation to accurately represent the intended experimental design, re-analysed via standardised pipelines that rely on open-source community developed tools. Each study's metadata are annotated using ontologies. The data are re-analyzed with the aim of reproducing the original conclusions of the underlying experiments. Expression Atlas is currently divided into Bulk Expression Atlas and Single Cell Expression Atlas. Expression Atlas contains data from differential studies (microarray and bulk RNA-Seq) and baseline studies (bulk RNA-Seq and proteomics), whereas Single Cell Expression Atlas is currently dedicated to Single Cell RNA-Sequencing (scRNA-Seq) studies. The resource has been in continuous development since 2009 and it is available at https://www.ebi.ac.uk/gxa.}, author = {Moreno, Pablo and Fexova, Silvie and George, Nancy and Manning, Jonathan R. and Miao, Zhichiao and Mohammed, Suhaib and Muñoz-Pomer, Alfonso and Fullgrabe, Anja and Bi, Yalan and Bush, Natassja and Iqbal, Haider and Kumbham, Upendra and Solovyev, Andrey and Zhao, Lingyun and Prakash, Ananth and García-Seisdedos, David and Kundu, Deepti J and Wang, Shengbo and Walzer, Mathias and Clarke, Laura and Osumi-Sutherland, David and Tello-Ruiz, Marcela Karey and Kumari, Sunita and Ware, Doreen and Eliasova, Jana and Arends, Mark J and Nawijn, Martijn C and Meyer, Kerstin and Burdett, Tony and Marioni, John and Teichmann, Sarah and Vizcaíno, Juan Antonio and Brazma, Alvis and Papatheodorou, Irene}, doi = {10.1093/nar/gkab1030}, journal = {Nucleic Acids Research}, month = {nov}, pages = {D129-D140}, title = {Expression Atlas update: gene and protein expression in multiple species}, url = {https://doi.org/10.1093/nar/gkab1030}, volume = {50}, year = {2021} }