@article{Uluduz2020, abstract = {Background. Early diagnosis of cerebral venous sinus thrombosis (CVST) associated with reproductive health-related risk factors (RHRF) including pregnancy, puerperium, and oral contraceptive (OC) use can prevent severe neurological sequelae; thus, the symptoms must be documented in detail for each group. Methods. Out of 1144 patients with CVST, a total of 777 women were enrolled from a multicenter for the study of cerebral venous sinus thrombosis (VENOST). Demographic, biochemical, clinical, and radiological aspects were compared for 324 cases with RHRF and 453 cases without RHRF. Results. The mean age of the RHRF (-) group (43.2 ± 13 years) was significantly higher than of the RHRF (+) group (34±9 years). A previous history of deep venous thrombosis (3%), isolated cavernous sinus involvement (1%), cranial neuropathy (13%), comorbid malignancy (7%), and its disability scores after 12 months (9%) were significantly higher in the RHRF (-) group. The RHRF (+) group consisted of 44% cases of puerperium, 33% cases of OC users and 23% of pregnant women. The mean age was found to be higher in OC users (38±9 years). A previous history of deep venous thrombosis was slightly higher in the pregnancy subgroup (4%). Epileptic seizures were more common in the puerperium group (44%). Conclusion. The results of our study indicate that the risk of CSVT increases parallel to age, OC use, and puerperium period. In addition, when considering the frequency of findings and symptoms, epileptic seizures in the puerperium subgroup of the RHRF (+) group and malignancies in the RHRF (-) group may accompany the CSVT. In daily practice, predicting these risks for the CSVT and early recognition of the symptoms will provide significant benefits to patients.}, author = {Uluduz, Derya and Sahin, Sevki and Duman, Taskin and Ozturk, Serefnur and Yayla, Vildan and Afsar, Nazire and Uzuner, Nevzat and Midi, Ipek and Cinar, Nilgun and Sungur, Mehmet Ali and Domac, Fusun Mayda and Ince, Birsen and Goksan, Baki and Misirli, Cemile Handan and Bakar, Mustafa and Kozak, Hasan Huseyin and Colakoglu, Sena and Karahan, Ali Yavuz and Goksu, Eylem Ozaydin and Ozdag, Fatih and Senol, Mehmet Guney and Yurekli, Vedat Ali and Aluclu, Ufuk and Demir, Serkan and Kucukoglu, Hayriye and Oruc, Serdar and Yesilot, Nilufer and Kusbeci, Ozge Yimaz and Nazliel, Bijen and Tokuc, Firdevs Ezgi Ucan and Bektas, Hesna and Tascilar, Fatma Nida and Aytac, Emrah and Gokce, Mustafa and Caglayan, Hale Zeynep Batur and Tufekci, Ahmet and Uzuner, Gulnur and Orken, Dilek Necioglu and Yalin, Osman Ozgur and Utku, Uygar and Yilmaz, Arda and Genc, Hamit and Cabalar, Murat and Milanlioglu, Aysel and Ekmekci, Hakan and Zeydan, Burcu and Baybas, Sevim and Kablan, Yuksel and Goksel, Basak Karakurum and Acikgoz, Mustafa and Kurucu, Hatice and Demirci, Seden and Gunes, Taskin}, doi = {10.1155/2020/8610903}, journal = {Stroke Research and Treatment}, month = {sep}, pages = {1-8}, title = {Cerebral Venous Sinus Thrombosis in Women: Subgroup Analysis of the VENOST Study}, url = {https://doi.org/10.1155/2020/8610903}, volume = {2020}, year = {2020} }