@article{Sewerin2019, abstract = {Objective.To assess associations of synovial perfusion, cartilage quality, and outcome in rheumatoid arthritis (RA).Methods.Synovial perfusion and cartilage quality were assessed by dynamic contrast-enhanced magnetic resonance imaging in metacarpophalangeal joints of 28 treatment-naive patients with RA at baseline and at 3 and 6 months after methotrexate. Analysis was by linear mixed modeling.Results.Synovial perfusion variables were associated with remission (p < 0.05) and cartilage quality (p < 0.004). Maximum synovial enhancement was associated to European League Against Rheumatism response (p < 0.05). Synovial perfusion improved in nonresponders over time (p < 0.05).Conclusion.Synovial perfusion relates to remission, response, and cartilage quality in a cohort of therapy-naive patients with early RA.}, author = {Sewerin, Philipp and Schleich, Christoph and Brinks, Ralph and Müller-Lutz, Anja and Fichter, Florian and Eichner, Markus and Schneider, Matthias and Ostendorf, Benedikt and Vordenbäumen, Stefan}, doi = {10.3899/jrheum.180832}, journal = {The Journal of Rheumatology}, month = {mar}, pages = {15-19}, title = {Assessing Associations of Synovial Perfusion, Cartilage Quality, and Outcome in Rheumatoid Arthritis Using Dynamic Contrast-enhanced Magnetic Resonance Imaging}, url = {https://oadoi.org/10.3899/jrheum.180832}, volume = {47}, year = {2019} }