@article{Manske2019, abstract = {Objective.We assessed construct validity of high-resolution peripheral quantitative computed tomography (HR-pQCT) joint space outcomes by comparison with radiographs in patients with rheumatoid arthritis.Methods.In 43 patients, quantitative, volumetric, HR-pQCT measurements were compared with ordinal Sharp/van der Heijde scoring (SvdH) in the 2nd and 3rd metacarpophalangeal joints.Results.Generalized estimating equations showed that joint space minimum, SD, and asymmetry by HR-pQCT were associated with SvdH scores (p < 0.05). There was a considerable range in HR-pQCT measurements at SvdH equal to 0.Conclusion.HR-pQCT demonstrated construct validity outcomes and provides improved 3-D visualization of joint space.}, author = {Manske, Sarah L. and Brunet, Scott C. and Finzel, Stephanie and Stok, Kathryn S. and Conaghan, Philip G. and Boyd, Steven K. and Barnabe, Cheryl}, doi = {10.3899/jrheum.180870}, journal = {The Journal of Rheumatology}, month = {jan}, pages = {1369-1373}, title = {The SPECTRA Collaboration OMERACT Working Group: Construct Validity of Joint Space Outcomes with High-resolution Peripheral Quantitative Computed Tomography}, url = {https://oadoi.org/10.3899/jrheum.180870}, volume = {46}, year = {2019} }