Diego Muñoz-Torrero

All papers authored by Diego Muñoz-Torrero

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2021 Caterina Pont

, Tiziana Ginex, Christian Griñán-Ferré, Matthias Scheiner, Alexia Mattellone, Noemí Martínez, Elsa M. Arce, Yolanda Soriano-Fernández, Marina Naldi, Angela De Simone, Marta Barenys, Jesús Gómez-Catalán, Belén Pérez, Raimon Sabate, Vincenza Andrisano

and 8 other authors

From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects

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2020 Elisabet Viayna, Nicolas Coquelle, Monika Cieslikiewicz-Bouet, Pedro Cisternas, Carolina A. Oliva, Elena Sánchez-López, Miren Ettcheto

, Manuela Bartolini

, Angela De Simone, Mattia Ricchini, Marisa Rendina, Mégane Pons, Omidreza Firuzi, Belén Pérez, Luciano Saso and 11 other authors

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

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F. Javier Pérez-Areales, María Garrido, Ester Aso, Manuela Bartolini

, Angela De Simone, Alba Espargaro, Tiziana Ginex, Raimon Sabaté

, Belén Pérez, Vincenza Andrisano

, Dolors Puigoriol-Illamola, Mercè Pallàs

, F. Javier Luque

, María Isabel Loza

, José M. Brea and 4 other authors

Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6

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This paper is made freely available by the publisher.

2019 Jean Jacques Vanden Eynde

, Arduino A. Mangoni

, Jarkko Rautio, Jérôme Leprince

, Yasu-Taka Azuma, Alfonso T. García-Sosa

, Christopher Hulme, Josef Jampilek

, Rafik Karaman

, Wei Li

, Paula A. C. Gomes

, Dimitra Hadjipavlou-Litina

, Raffaele Capasso

, Athina Geronikaki, Laura Cerchia

and 27 other authors

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6

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F. Javier Pérez-Areales, Andreea L. Turcu, Marta Barniol-Xicota, Caterina Pont, Deborah Pivetta, Alba Espargaró, Manuela Bartolini

, Angela De Simone, Vincenza Andrisano, Belén Pérez, Raimon Sabate, Francesc X. Sureda

, Santiago Vázquez

, Diego Muñoz-Torrero

A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors

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2018 Arduino Mangoni

, Catherine Guillou

, Jean Vanden Eynde

, Christopher Hulme, Josef Jampilek

, Wei Li

, Katalin Prokai-Tatrai

, Jarkko Rautio

, Simona Collina

, Tiziano Tuccinardi

, Maria Sousa

, Jean-Marc Sabatier

, Stefania Galdiero

, Rafik Karaman

, George Kokotos

and 10 other authors

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–4

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Arduino Mangoni

, Maria de Sousa, Tiziano Tuccinardi

, Simona Collina

, Jean Vanden Eynde

, Diego Muñoz-Torrero

, Rafik Karaman

, Carlo Siciliano

, Katalin Prokai-Tatrai

, Jarkko Rautio, Catherine Guillou

, Michael Gütschow

, Stefania Galdiero

, Hong Liu, Luigi Agrofoglio

and 5 other authors

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-3

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Carles Galdeano, Nicolas Coquelle, Monika Cieslikiewicz-Bouet, Manuela Bartolini, Belén Pérez, M. Clos, Israel Silman, Ludovic Jean

, Jacques-Philippe Colletier, Pierre-Yves Renard, Diego Muñoz-Torrero

Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis

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2017 Diego Muñoz-Torrero

, Maria de Sousa, Arduino Mangoni

, Hong Liu, Christopher Hulme, Jarkko Rautio

, Rafik Karaman

, Katalin Prokai-Tatrai

, Jean-Marc Sabatier

, Carlo Siciliano

, F. Luque

, George Kokotos

, Rino Ragno

, Simona Collina

, Catherine Guillou

and 2 other authors

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–2

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Diego Muñoz-Torrero

, Arduino Mangoni

, Catherine Guillou

, Simona Collina

, Jean Jacques Vanden Eynde

, Jarkko Rautio

, György Keserű

, Christopher Hulme, Kelly Chibale, F. Luque

, Rafik Karaman

, Michael Gütschow

, Hong Liu, Rino Ragno

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes

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Alba Espargaró, Tiziana Ginex

, Maria del Mar Vadell, Maria A. Busquets, Joan Estelrich, Diego Muñoz-Torrero

, F. Javier Luque

, Raimon Sabate

Combined in Vitro Cell-Based/in Silico Screening of Naturally Occurring Flavonoids and Phenolic Compounds as Potential Anti-Alzheimer Drugs

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2016 Michael Decker, Diego Muñoz-Torrero

Special Issue: “Molecules against Alzheimer”

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This paper is available in a repository.

Irene Sola, Albert Artigas

, Martin C. Taylor, F. Javier Pérez-Areales

, Elisabet Viayna, M. Victòria Clos, Belén Pérez, Colin W. Wright, John M. Kelly, Diego Muñoz-Torrero

Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents

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Alba Espargaró, Aina Medina, Ornella Di Pietro, Diego Muñoz-Torrero

, Raimon Sabate

Ultra rapid in vivo screening for anti-Alzheimer anti-amyloid drugs

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2015 Susanna Navarro, Anita Carija

, Diego Muñoz-Torrero

, Salvador Ventura

A fast and specific method to screen for intracellular amyloid inhibitors using bacterial model systems

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

Irene Sola, Ester Aso, Daniela Frattini, Irene López-González, Alba Espargaró, Raimon Sabaté, Ornella Di Pietro, F. Javier Luque, M. Victòria Clos, Isidro Ferrer, Diego Muñoz-Torrero

Novel Levetiracetam Derivatives That Are Effective against the Alzheimer-like Phenotype in Mice: Synthesis, in Vitro, ex Vivo, and in Vivo Efficacy Studies

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L. Giménez-Llort, M. Ratia, B. Pérez, P. Camps, D. Muñoz-Torrero

, A. Badia, M. V. Clos

AVCRI104P3, a novel multitarget compound with cognition-enhancing and anxiolytic activities: Studies in cognitively poor middle-aged mice

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Irene Sola, Elisabet Viayna, Tània Gómez, Carles Galdeano, Matteo Cassina, Pelayo Camps, Margherita Romeo

, Luisa Diomede, Mario Salmona, Pilar Franco, Mireille Schaeffer, Diego Colantuono, David Robin, Daniela Brunner, Nicole Taub and 2 other authors

Multigram Synthesis and in Vivo Efficacy Studies of a Novel Multitarget Anti-Alzheimer’s Compound

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2014 F. Javier Pérez-Areales

, Ornella Di Pietro, Alba Espargaró, Anna Vallverdú-Queralt

, Carles Galdeano, Ilaria M. Ragusa, Elisabet Viayna, Catherine Guillou

, M. Victòria Clos, Belén Pérez, Raimon Sabaté, Rosa M. Lamuela-Raventós, F. Javier Luque, Diego Muñoz-Torrero

Shogaol-huprine hybrids: Dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.

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Ornella Di Pietro, F. Javier Pérez-Areales

, Jordi Juárez-Jiménez, Alba Espargaró, M. Victòria Clos, Belén Pérez, Rodolfo Lavilla, Raimon Sabaté, F. Javier Luque, Diego Muñoz-Torrero

Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies

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All papers authored by Diego Muñoz-Torrero