Evette Radisky - Dissemin

All papers authored by Evette Radisky

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2023 Alessandro Bonadio

, Bernhard L. Wenig, Alexandra Hockla, Evette S. Radisky

Designed Loop Extension Followed by Combinatorial Screening Confers High Specificity to a Broad Matrix Metalloproteinase Inhibitor

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2022 Alessandro Bonadio, Bernhard L. Wenig, Alexandra Hockla, Evette S. Radisky

, Julia M. Shifman

A broad matrix metalloproteinase inhibitor with designed loop extension exhibits ultrahigh specificity for MMP-14

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This paper is made freely available by the publisher.

Christine Mehner, Alexandra Hockla, Mathew Coban

, Benjamin Madden, Rosendo Estrada, Derek C. Radisky, Evette S. Radisky

Activity-based protein profiling reveals active serine proteases that drive malignancy of human ovarian clear cell carcinoma

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Paula Duch

, Natalia Díaz-Valdivia, Rafael Ikemori

, Marta Gabasa, Evette S. Radisky

, Marselina Arshakyan

, Sabrina Gea-Sorlí, Anna Mateu-Bosch, Paloma Bragado, Josep Lluís Carrasco, Hidetoshi Mori, Josep Ramírez, Cristina Teixidó

, Noemí Reguart, Cristina Fillat and 2 other authors

Aberrant TIMP-1 overexpression in tumor-associated fibroblasts drives tumor progression through CD63 in lung adenocarcinoma

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Maryam Raeeszadeh-Sarmazdeh, Mathew Coban

, Shivansh Mahajan, Alexandra Hockla, Banumathi Sankaran, Gregory P. Downey, Derek C. Radisky, Evette S. Radisky

Engineering of tissue inhibitor of metalloproteinases TIMP-1 for fine discrimination between closely related stromelysins MMP-3 and MMP-10

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2021 Yu Shrike Zhang

, Carla M. Weisend

, Mathew A. Coban

, Sushila Maharjan

, Juliet Morrison

, David Hyram Hernandez Medina

, Wanlu Li, William D. Freeman, Evette S. Radisky

, Karine G. Le Roch, Karine Le Roch, Hideki Ebihara

, Thomas R. Caulfield

Attacking COVID-19 Progression Using Multi-Drug Therapy for Synergetic Target Engagement

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2020 Michael Heyne, Jason Shirian, Itay Cohen, Yoav Peleg, Evette S. Radisky

, Niv Papo, Julia M. Shifman

Climbing up and down binding landscapes: a high-throughput study of mutational effects in homologous protein-protein complexes

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Christine Mehner, Erin Miller, Alexandra Hockla, Mathew Coban

, S. John Weroha, Derek C. Radisky, Evette S. Radisky

Targeting an autocrine IL-6–SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma

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Mathew Coban, Juliet Morrison, William Freeman, Evette S. Radisky

, Karine Le Roch, Thomas Caulfield

Targeting Tmprss2, S-protein:Ace2, and 3CLpro for Synergetic Inhibitory Engagement

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2019 Fu Gui, Yuebo Zhang, Jianhua Wan, Xianbao Zhan

, Yao Yao, Yinghua Li, Ashley N. Haddock, Ji Shi, Jia Guo, Jiaxiang Chen

, Xiaohui Zhu, Brandy H. Edenfield, Lu Zhuang, Cheng Hu, Ying Wang and 7 other authors

Trypsin activity governs increased susceptibility to pancreatitis in mice expressing human PRSS1R122H

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Maryam Raeeszadeh-Sarmazdeh, Kerrie A. Greene, Banumathi Sankaran, Gregory P. Downey, Derek C. Radisky, Evette S. Radisky

Directed evolution of the metalloproteinase inhibitor TIMP-1 reveals that its N- and C-terminal domains cooperate in matrix metalloproteinase recognition

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Honghai Ma, Alexandra Hockla, Christine Mehner, Matt Coban, Niv Papo, Derek C. Radisky, Evette S. Radisky

PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are associated with poor prognosis and contribute to tumor cell invasion and growth in lung adenocarcinoma

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Zsanett Jancsó, Grzegorz Oracz, Aleksandra Anna Kujko, Eliwira Kolodziejczyk, Evette S. Radisky

, Agnieszka Magdalena Rygiel, Miklós Sahin-Tóth

Novel Pathogenic PRSS1 Variant p.Glu190Lys in a Case of Chronic Pancreatitis

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Christine Mehner, Evette S. Radisky

Bad Tumors Made Worse: SPINK1

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Itay Cohen, Matt Coban, Anat Shahar, Banumathi Sankaran, Alexandra Hockla, Shiran Lacham, Thomas R. Caulfield, Evette S. Radisky

, Niv Papo

Disulfide engineering of human Kunitz-type serine protease inhibitors enhances proteolytic stability and target affinity toward mesotrypsin

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2018 Si Naftaly, Itay Cohen, Anat Shahar, Alexandra Hockla, Evette S. Radisky

, Niv Papo

Mapping protein selectivity landscapes using multi-target selective screening and next-generation sequencing of combinatorial libraries

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Valeria Arkadash, Evette S. Radisky

, Niv Papo

Combinatorial engineering of N-TIMP2 variants that selectively inhibit MMP9 and MMP14 function in the cell

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Itay Cohen, Si Naftaly, Efrat Ben-Zeev, Alexandra Hockla, Evette S. Radisky

, Niv Papo

Pre-equilibrium competitive library screening for tuning inhibitor association rate and specificity toward serine proteases

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Jason Shirian, Valeria Arkadash, Itay Cohen, Tamila Sapir, Evette S. Radisky

, Niv Papo, Julia M. Shifman

Converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of MMP-9 and MMP-14

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All papers authored by Evette Radisky