Konstantinos Koussis - Dissemin

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All papers authored by Konstantinos Koussis

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2021 Elina Lidumniece, Chrislaine Withers-Martinez

ORCID

, Fiona Hackett, Christine R. Collins

ORCID

, Abigail J. Perrin

ORCID

, Konstantinos Koussis

ORCID

, Claudine Bisson

ORCID

, Michael J. Blackman

ORCID

, Aigars Jirgensons

ORCID

Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1

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Michele S. Y. Tan

ORCID

, Konstantinos Koussis

ORCID

, Chrislaine Withers‐Martinez, Steven A. Howell, James A. Thomas

ORCID

, Fiona Hackett, Ellen Knuepfer, Min Shen, Matthew D. Hall, Ambrosius P. Snijders, Michael J. Blackman

ORCID

Autocatalytic activation of a malarial egress protease is druggable and requires a protein cofactor

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Aurélia C. Balestra

ORCID

, Konstantinos Koussis

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, Natacha Klages, Steven A. Howell, Helen R. Flynn

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, Marcus Bantscheff

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, Carla Pasquarello, Abigail J. Perrin

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, Lorenzo Brusini

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, Patrizia Arboit, Olalla Sanz

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, Laura Peces-Barba Castaño

ORCID

, Chrislaine Withers-Martinez

ORCID

, Alexandre Hainard, Sonja Ghidelli-Disse

ORCID

and 4 other authors

Ca ²⁺ signals critical for egress and gametogenesis in malaria parasites depend on a multipass membrane protein that interacts with PKG

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2020 Jim Aitken, Catherine Moore, David Moore, Eleni Nastouli, Jerome Nicod, Luke Nightingale, Jessica Olsen, Nicola O’Reilly, Amar Pabari, Venizelos Papayannopoulos, Namita Patel, Nigel Peat, Marc Pollitt, Peter Ratcliffe, Caetano Reis e. Sousa and 265 other authors

Scalable and robust SARS-CoV-2 testing in an academic center.

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Aurélia C. Balestra, Konstantinos Koussis

ORCID

, Natacha Klages, Steven A. Howell, Helen R. Flynn, Marcus Bantscheff, Carla Pasquarello, Abigail J. Perrin, Lorenzo Brusini, Patrizia Arboit, Olalla Sanz, Laura Peces-Barba Castaño, Chrislaine Withers-Martinez, Alexandre Hainard, Sonja Ghidelli-Disse and 4 other authors

A multipass membrane protein interacts with the cGMP-dependent protein kinase to regulate critical calcium signals in malaria parasites

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Konstantinos Koussis

ORCID

, Chrislaine Withers-Martinez, David A. Baker, Michael J. Blackman

ORCID

Simultaneous multiple allelic replacement in the malaria parasite enables dissection of PKG function

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Sarah J. Tarr, Chrislaine Withers-Martinez, Helen R. Flynn, Ambrosius P. Snijders, Laura Masino, Konstantinos Koussis

ORCID

, David J. Conway, Michael J. Blackman

ORCID

A malaria parasite subtilisin propeptide-like protein is a potent inhibitor of the egress protease SUB1

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2018 Trias Thireou, Georgia Kythreoti, Katerina E. Tsitsanou, Konstantinos Koussis

ORCID

, Christina E. Drakou, Julie Kinnersley, Thomas Kröber, Patrick M. Guerin, Jing-Jiang Zhou, Kostas Iatrou, Elias Eliopoulos, Spyros E. Zographos

Identification of novel bioinspired synthetic mosquito repellents by combined ligand-based screening and OBP-structure-based molecular docking

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Thomas Kröber

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, Konstantinos Koussis

ORCID

, Martine Bourquin, Panagiota Tsitoura, Maria Konstantopoulou, Taiwo Sam Awolola, Francesca R. Dani

ORCID

, Huili Qiao, Paolo Pelosi, Kostas Iatrou, Patrick M. Guerin

Odorant-binding protein-based identification of natural spatial repellents for the African malaria mosquito Anopheles gambiae

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Evi Goulielmaki, Sofia Kaforou, Kannan Venugopal, Thanasis G. Loukeris, Inga Siden-Kiamos, Konstantinos Koussis

ORCID

Distinct effects of HIV protease inhibitors and ERAD inhibitors on zygote to ookinete transition of the malaria parasite

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2017 Konstantinos Koussis

ORCID

, Evi Goulielmaki, Anna Chalari, Chrislaine Withers-Martinez, Inga Siden-Kiamos, Kai Matuschewski

ORCID

, Thanasis G. Loukeris

Targeted Deletion of a Plasmodium Site-2 Protease Impairs Life Cycle Progression in the Mammalian Host

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2015 Zoi Tampaki, Ramadhan S. Mwakubambanya, Evi Goulielmaki, Sofia Kaforou, Kami Kim, Andrew P. Waters, Vern B. Carruthers, Inga Siden-Kiamos, Thanasis G. Loukeris, Konstantinos Koussis

ORCID

Ectopic Expression of a Neospora caninum Kazal Type Inhibitor Triggers Developmental Defects in Toxoplasma and Plasmodium

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Panagiota Tsitoura, Konstantinos Koussis

ORCID

, Kostas Iatrou

Inhibition of Anopheles gambiae Odorant Receptor Function by Mosquito Repellents

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2012 Chrislaine Withers-Martinez, Catherine Suarez, Simone Fulle, Samir Kher, Maria Penzo, Jean-Paul Ebejer, Kostas Koussis

ORCID

, Fiona Hackett, Aigars Jirgensons, Paul Finn, Michael J. Blackman

Plasmodium subtilisin-like protease 1 (SUB1): Insights into the active-site structure, specificity and function of a pan-malaria drug target

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2011 K. E. Tsitsanou, T. Thireou, C. E. Drakou, K. Koussis

ORCID

, M. V. Keramioti, D. D. Leonidas, E. Eliopoulos, K. Iatrou, S. E. Zographos

Anopheles gambiae odorant binding protein crystal complex with the synthetic repellent DEET: implications for structure-based design of novel mosquito repellents

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2009 Konstantinos Koussis

ORCID

, Chrislaine Withers-Martinez, Sharon Yeoh, Matthew Child, Fiona Hackett, Ellen Knuepfer, Luiz Juliano, Ute Woehlbier, Hermann Bujard, Michael J. Blackman

A multifunctional serine protease primes the malaria parasite for red blood cell invasion

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2008 Timothy J. Dowse, Konstantinos Koussis

ORCID

, Michael J. Blackman, Dominique Soldati-Favre

Roles of Proteases during Invasion and Egress by Plasmodium and Toxoplasma

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2007 Sharon Yeoh, Rebecca A. O'Donnell, Konstantinos Koussis

ORCID

, Anton R. Dluzewski, Keith H. Ansell, Simon A. Osborne, Fiona Hackett, Chrislaine Withers-Martinez, Graham H. Mitchell, Lawrence H. Bannister, Justin S. Bryans, Catherine A. Kettleborough, Michael J. Blackman

Subcellular Discharge of a Serine Protease Mediates Release of Invasive Malaria Parasites from Host Erythrocytes

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