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All papers authored by Emma Sierecki

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2023 Winnie Luu, Bitong Li

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ORCID

, Mehdi Moustaqil, Emmanuelle Lesieur, Renae Skoczylas, Valerie Kouskoff, Emma Sierecki

ORCID

, Tara Davidson, Richard Harwood, Keyi Jiang, Jan Kazenwadel

ORCID

, Ivy Kn N. Chiang, Matthew S. Graus, Nils Kirschnick and 6 other authors

The blood vasculature instructs lymphatic patterning in a SOX7‐dependent manner

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2021 Alex J. McCann

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, Jieqiong Lou, Mehdi Moustaqil, Matthew S. Graus, Ailisa Blum

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, Frank Fontaine, Hui Liu, Winnie Luu, Paulina Rudolffi-Soto, Peter Koopman, Emma Sierecki

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, Yann Gambin, Frédéric A. Meunier, Zhe Liu, Elizabeth Hinde and 1 other authors

A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity

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André D. G. Leitão

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, Paulina Rudolffi-Soto

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, Alexandre Chappard

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, Akshay Bhumkar, Derrick Lau

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, Dominic J. B. Hunter, Yann Gambin

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, Emma Sierecki

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Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein

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Kerrie-Ann McMahon

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, David A. Stroud, Yann Gambin

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, Vikas A. Tillu

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, Michele Bastiani, Emma Sierecki

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, Mark E. Polinkovsky, Thomas E. Hall

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, Guillermo A. Gomez, Yeping Wu, Marie-Odile Parat, Nick Martel, Harriet P. Lo, Kum Khanna, Kirill Alexandrov and 4 other authors

Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

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Max T. B. Clabbers

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, Susannah Holmes, Timothy W. Muusse

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, Parimala R. Vajjhala, Sara J. Thygesen, Alpeshkumar K. Malde

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, Dominic J. B. Hunter, Tristan I. Croll, Leonie Flueckiger, Jeffrey D. Nanson

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, M.-D. Habibur Rahaman, M. Habibur Rahaman, Andrew Aquila

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, Mark S. Hunter

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, Mengning Liang and 11 other authors

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

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Akshay Bhumkar, Chloe Magnan, Derrick Lau, Eugene Soh Wei Jun, Nicolas Dzamko, Yann Gambin

ORCID

, Emma Sierecki

ORCID

Single‐Molecule Counting Coupled to Rapid Amplification Enables Detection of α‐Synuclein Aggregates in Cerebrospinal Fluid of Parkinson's Disease Patients

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Derrick Lau

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, James C. Walsh, Claire F. Dickson, Andrew Tuckwell, Jeffrey H. Stear, Dominic J. B. Hunter, Akshay Bhumkar, Vaibhav Shah, Stuart G. Turville, Emma Sierecki

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, Yann Gambin, Till Böcking

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, David A. Jacques

Rapid HIV-1 Capsid Interaction Screening Using Fluorescence Fluctuation Spectroscopy

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I. K.-N. Chiang, W. Luu, K. Jiang, N. Kirschnick, M. Moustaqil, T. Davidson, E. Lesieur, R. Skoczylas, Kouskoff, J. Kazenwadel, L. Arriola-Martinez, E. Sierecki

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, Y. Gambin, K. Alitalo, F. Kiefer and 2 other authors

The blood vasculature instructs lymphatics patterning in a SOX7 dependent manner

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Derrick Lau, Chloé Magnan, Kathryn Hill, Antony Cooper, Yann Gambin, Emma Sierecki

ORCID

Single molecule fingerprinting reveals different amplification properties of α-synuclein oligomers and preformed fibrils in seeding assay

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A. D. G. Leitão, P. R. Soto, A. Chappard, A. Bhumkar, D. J. B. Hunter, E. Sierecki

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, Y. Gambin

Selectivity of protein interactions along the aggregation pathway of α-synuclein

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2020 Mehdi Moustaqil, Emma Ollivier

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, Hsin-Ping Chiu, Sarah Van Tol, Paulina Rudolffi-Soto, Christian Stevens, Akshay Bhumkar, Dominic J. B. Hunter, Alexander N. Freiberg, David Jacques, Benhur Lee

ORCID

, Emma Sierecki

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, Yann Gambin

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.

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Nirukshan Shanmugam, Max O. D. G. Baker, Maximo Sanz-Hernandez, Emma Sierecki

ORCID

, Yann Gambin, Megan Steain, Chi L. L. Pham, Margaret Sunde

Herpes simplex virus encoded ICP6 protein forms functional amyloid assemblies with necroptosis-associated host proteins

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Mehdi Moustaqil, Yann Gambin, Emma Sierecki

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Biophysical Techniques for Target Validation and Drug Discovery in Transcription-Targeted Therapy

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Megan Steain

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, Max O. D. G. Baker, Chi L. L. Pham, Nirukshan Shanmugam, Yann Gambin, Emma Sierecki

ORCID

, Brian P. McSharry

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, Selmir Avdic, Barry Slobedman

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, Margaret Sunde

ORCID

, Allison Abendroth

ORCID

Varicella zoster virus encodes a viral decoy RHIM to inhibit cell death

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Emma Sierecki

ORCID

, Yann Gambin

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B. Meyer, J. Chiaravalli, S. Gellenoncourt, P. Brownridge, D. P. Bryne, L. A. Daly, A. Grauslys, M. Walter, F. Agou, L. A. Chakrabarti, C. S. Craik, C. E. Eyers, P. A. Eyers, Y. Gambin, A. R. Jones and 4 other authors

Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets for drug repurposing

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This paper was not found in any repository; the policy of its publisher is unknown or unclear.

M. Moustaqil, E. Ollivier, H.-P. Chiu, S. van Tol, P. Rudolffi-Soto, C. Stevens, A. Bhumkar, D. J. B. Hunter, A. Freiberg, D. Jacques, B. Lee, E. Sierecki

ORCID

, Y. Gambin

SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): Implications for disease presentation across species and the search for reservoir hosts.

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2019 James W. P. Brown, Arnaud Bauer, Mark E. Polinkovsky, Akshay Bhumkar, Dominic J. B. Hunter, Katharina Gaus, Emma Sierecki

ORCID

, Yann Gambin

Single-molecule detection on a portable 3D-printed microscope

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Emma Sierecki

ORCID

A Novel Split Reporter Uncages New Possibilities

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Siew Pang, Charles Bayly-Jones, Mazdak Radjainia, Bradley A. Spicer, Ruby H. P. Law

ORCID

, Adrian W. Hodel, Edward S. Parsons, Susan M. Ekkel, Paul J. Conroy

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ORCID

, Hariprasad Venugopal, Phillip I. Bird

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, Bart W. Hoogenboom

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, Ilia Voskoboinik

ORCID

, Yann Gambin and 3 other authors

The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1

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