Researcher
John Harling
GlaxoSmithKline Research and Development
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7 papers found
All papers authored by John Harling
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2023
Rebecca Stevens 
,
Enrique Bendito-Moll,
David J. Battersby,
Afjal H. Miah,
Natalie Wellaway,
Robert P. Law ,
Peter Stacey,
Diana Klimaszewska,
Justyna M. Macina,
Glenn A. Burley ,
John D. Harling
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,
Enrique Bendito-Moll,
David J. Battersby,
Afjal H. Miah,
Natalie Wellaway,
Robert P. Law ,
Peter Stacey,
Diana Klimaszewska,
Justyna M. Macina,
Glenn A. Burley ,
John D. Harling
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2022
Qisi Zhang ,
Cyrille S. Kounde ,
Milon Mondal ,
Jake L. Greenfield ,
Jennifer R. Baker ,
Sergei Kotelnikov ,
Mikhail Ignatov,
Christopher P. Tinworth ,
Leran Zhang ,
Daniel Conole ,
Elena De Vita ,
Dima Kozakov ,
Adam McCluskey ,
John D. Harling ,
Matthew J. Fuchter
and 1 other authors
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,
Cyrille S. Kounde ,
Milon Mondal ,
Jake L. Greenfield ,
Jennifer R. Baker ,
Sergei Kotelnikov ,
Mikhail Ignatov,
Christopher P. Tinworth ,
Leran Zhang ,
Daniel Conole ,
Elena De Vita ,
Dima Kozakov ,
Adam McCluskey ,
John D. Harling ,
Matthew J. Fuchter
and 1 other authors
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2021
Robert P. Law ,
Joao Nunes,
Chun‐wa Chung ,
Marcus Bantscheff ,
Karol Buda ,
Han Dai,
John P. Evans,
Adam Flinders ,
Diana Klimaszewska,
Antonia J. Lewis,
Marcel Muelbaier,
Paul Scott‐Stevens,
Peter Stacey,
Christopher J. Tame,
Gillian F. Watt
and 4 other authors
,
Joao Nunes,
Chun‐wa Chung ,
Marcus Bantscheff ,
Karol Buda ,
Han Dai,
John P. Evans,
Adam Flinders ,
Diana Klimaszewska,
Antonia J. Lewis,
Marcel Muelbaier,
Paul Scott‐Stevens,
Peter Stacey,
Christopher J. Tame,
Gillian F. Watt
and 4 other authors
Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs
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Afjal H. Miah,
Ian E. D. Smith,
Mark Rackham,
Alina Mares,
Aditya R. Thawani ,
Rakesh Nagilla,
Pamela A. Haile ,
Bartholomew J. Votta,
Laurie J. Gordon,
Gillian Watt,
Jane Denyer,
Don T. Fisher,
Phoebe Dace,
Paul Giffen,
Andrea Goncalves
and 3 other authors
,
Rakesh Nagilla,
Pamela A. Haile ,
Bartholomew J. Votta,
Laurie J. Gordon,
Gillian Watt,
Jane Denyer,
Don T. Fisher,
Phoebe Dace,
Paul Giffen,
Andrea Goncalves
and 3 other authors
Optimization of a Series of RIPK2 PROTACs
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2020
Chun-Wa Chung ,
Han Dai,
Esther Fernandez ,
Christopher P. Tinworth ,
Ian Churcher ,
Jenni Cryan,
Jane Denyer,
John D. Harling ,
Agnieszka Konopacka,
Markus A. Queisser ,
Christopher J. Tame,
Gillian Watt,
Fan Jiang,
Dongming Qian,
Andrew B. Benowitz
,
Han Dai,
Esther Fernandez ,
Christopher P. Tinworth ,
Ian Churcher ,
Jenni Cryan,
Jane Denyer,
John D. Harling ,
Agnieszka Konopacka,
Markus A. Queisser ,
Christopher J. Tame,
Gillian Watt,
Fan Jiang,
Dongming Qian,
Andrew B. Benowitz
Structural insights into PROTAC-mediated degradation of Bcl-xL
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Alina Mares,
Afjal H. Miah,
Ian E. D. Smith,
Mark Rackham,
Aditya R. Thawani ,
Jenni Cryan,
Pamela A. Haile,
Bartholomew J. Votta,
Allison M. Beal,
Carol Capriotti,
Michael A. Reilly,
Don T. Fisher,
Nico Zinn,
Marcus Bantscheff ,
Thomas T. MacDonald
and 8 other authors
,
Jenni Cryan,
Pamela A. Haile,
Bartholomew J. Votta,
Allison M. Beal,
Carol Capriotti,
Michael A. Reilly,
Don T. Fisher,
Nico Zinn,
Marcus Bantscheff ,
Thomas T. MacDonald
and 8 other authors
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2
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