Sofia Benfeito
0000-0001-9645-8152
Universidade do Porto Faculdade de Ciências
81 papers found
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Unraveling the In Vitro Toxicity Profile of Psychedelic 2C Phenethylamines and Their N-Benzylphenethylamine (NBOMe) Analogues
Modulating Cytotoxicity with Lego-like Chemistry: Upgrading Mitochondriotropic Antioxidants with Prototypical Cationic Carrier Bricks
Cytotoxicity and Mitochondrial Effects of Phenolic and Quinone-Based Mitochondria-Targeted and Untargeted Antioxidants on Human Neuronal and Hepatic Cell Lines: A Comparative Analysis
A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients
Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases
Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts
Lipid Nanosystems and Serum Protein as Biomimetic Interfaces: Predicting the Biodistribution of a Caffeic Acid-Based Antioxidant
Mitochondriotropic antioxidants as novel therapeutics for Amyotrophic lateral sclerosis: development of multitarget agents to prevent stress induced motor neuron death (BEST POSTER)
Exploring the Multi-Target Performance of Mitochondriotropic Antioxidants against the Pivotal Alzheimer’s Disease Pathophysiological Hallmarks
Antioxidant Therapy and Neurodegenerative Disorders: Lessons From Clinical Trials
Antioxidant therapy, oxidative stress, and blood-brain barrier: The road of dietary antioxidants
Bioavailability improvement of a monoamine oxidase-B inhibitor using PEGylated PCL-based nanoparticles
Boosting Drug Discovery for Parkinson’s: Enhancement of the Delivery of a Monoamine Oxidase-B Inhibitor by Brain-Targeted PEGylated Polycaprolactone-Based Nanoparticles
Development of new antibiotics based on natural scaffolds
Redox signaling and metabolism modulation of human fibriblasts by mitochondria-targeted polyphenolic constructs
Unraveling the mechanism throughout mitochondriotropic cinnamic acid antioxidants increase cellular stress response in HepG2 cells
Human skin fibroblasts from sporadic Parkinsons disease patients as a surrogate to measure the efficacy of a novel mitochondria-directed antioxidant therapy
Design and synthesis of mitochondriotropic antioxidants based on dietary scaffold endowed with neuroprotective activity and BBB permeability
Mitochondriotropic antioxidants based on dietary phenolic acids: Potential effect against chemical-induced skin senescence
Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction
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