All papers authored by Brian Kobilka
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Anne Stößel,
Luis Maul ,
Daniel Mayer,
Harald Hübner ,
Kunio Hirata ,
A. J. Venkatakrishnan,
Ron O. Dror ,
Brian K. Kobilka ,
Roger K. Sunahara ,
Xiangyu Liu ,
Peter Gmeiner
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Anne Stößel,
Luis Maul ,
Daniel Mayer,
Harald Hübner ,
Kunio Hirata ,
A. J. Venkatakrishnan,
Ron O. Dror ,
Brian K. Kobilka ,
Roger K. Sunahara ,
Xiangyu Liu ,
Peter Gmeiner
Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics
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Qinggong Wang,
Harald Hübner ,
Yunfei Hu,
Xiaogang Niu,
Haoqing Wang,
Shoji Maeda ,
Asuka Inoue ,
Yuyong Tao ,
Peter Gmeiner ,
Yang Du ,
Changwen Jin ,
Brian K. Kobilka
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Haoqing Wang,
Saheem A. Zaidi,
Jeffrey F. DiBerto ,
Tao Che ,
Qianhui Qu ,
Michael J. Robertson ,
Manish K. Madasu,
Amal El Daibani,
Balazs R. Varga,
Tiffany Zhang,
Claudia Ruiz,
Shan Liu,
Jin Xu,
Kevin Appourchaux
and 11 other authors
Structure-based design of bitopic ligands for the µ-opioid receptor
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,
Weijiao Huang,
Deniz Aydin,
Joseph M. Paggi,
Alpay B. Seven,
Haoqing Wang,
Soumen Chakraborty,
Tao Che ,
Jeffrey F. DiBerto ,
Michael J. Robertson ,
Asuka Inoue ,
Carl-Mikael Suomivuori ,
Bryan L. Roth ,
Susruta Majumdar ,
Ron O. Dror
and 2 other authors
Insights into distinct signaling profiles of the µOR activated by diverse agonists
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Kaavya Krishna Kumar ,
Hongli Hu ,
Mie Fabricius Pedersen,
Evan S. O’Brien ,
Lise Giehm ,
Christine Jennings ,
Gözde Eskici ,
Asuka Inoue,
Michael Lerch ,
Jesper Mosolff Mathiesen ,
Georgios Skiniotis ,
Brian K. Kobilka
Structural insights into differences in G protein activation by family A and family B GPCRs
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,
Jonas Kaindl ,
Magdalena Korczynska,
Anne Stößel,
Daniela Dengler,
Markus Stanek,
Harald Hübner,
Mary J. Clark ,
Jake Mahoney,
Rachel Ann Matt ,
Xinyu Xu,
Kunio Hirata ,
Brian K. Shoichet ,
Roger K. Sunahara ,
Brian K. Kobilka
and 1 other authors
An allosteric modulator binds to a conformational hub in the β2 adrenergic receptor
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Jiawei Zhao,
Xiaoou Sun,
Jun Xu ,
Peter Gmeiner ,
Hong-Wei Wang ,
Brian K. Kobilka
Activation of the α2B adrenoceptor by the sedative sympatholytic dexmedetomidine
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Ali Masoudi ,
Alem W. Kahsai ,
Li-Yin Huang ,
Biswaranjan Pani ,
Dean P. Staus,
Paul J. Shim ,
Kunio Hirata ,
Rishabh K. Simhal,
Allison M. Schwalb,
Paula K. Rambarat ,
Seungkirl Ahn,
Robert J. Lefkowitz ,
Brian Kobilka
Mechanism of β 2 AR regulation by an intracellular positive allosteric modulator
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Lubna Ghani ,
Yang Du ,
Parameswaran Hariharan ,
Jonas S. Mortensen ,
Orquidea Ribeiro ,
Hongli Hu ,
Georgios Skiniotis ,
Claus J. Loland ,
Lan Guan ,
Brian K. Kobilka ,
Bernadette Byrne ,
Pil Seok Chae
New penta-saccharide-bearing tripod amphiphiles for membrane protein structure studies
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