Jean-Yves Winum - Dissemin

Papers authored by Jean-Yves Winum

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2009 J.-Y. Winum

, C. T. Supuran

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2008 M. Stitti, Maamar Stiti, Alessandro Cecchi, Marouan Rami, Mohamed Abdaoui, Véronique Barragan-Montero, Andrea Scozzafava, Yannick Guari, Jean-Yves Winum

, Claudiu T. Supuran

Carbonic Anhydrase Inhibitor Coated Gold Nanoparticles Selectively Inhibit the Tumor-Associated Isoform IX over the Cytosolic Isozymes I and II

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Fatma-Zohra Smaine, Fabio Pacchiano, Marouan Rami, Véronique Barragan-Montero, Daniela Vullo, Andrea Scozzafava, Jean-Yves Winum

, Claudiu T. Supuran

Carbonic anhydrase inhibitors: 2-Substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV

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Marouan Rami, Alessandro Cecchi, Jean-Louis Montero, Alessio Innocenti, Daniela Vullo, Andrea Scozzafava, Jean-Yves Winum

, Claudiu T. Supuran

Carbonic Anhydrase Inhibitors: Design of Membrane-Impermeant Copper(II) Complexes of DTPA-, DOTA-, and TETA-Tailed Sulfonamides Targeting the Tumor-Associated Transmembrane Isoform IX

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Alessandro Cecchi, Laura Ciani, Jean-Yves Winum

, Jean-Louis Montero, Andrea Scozzafava, Sandra Ristori, Claudiu T. Supuran

Carbonic anhydrase inhibitors: Design of spin-labeled sulfonamides incorporating TEMPO moieties as probes for cytosolic or transmembrane isozymes

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Jean-Louis Montero, Claudiu Supuran, Andrea Scozzafava, Jean-Yves Winum

Design of Zinc Binding Functions for Carbonic Anhydrase Inhibitors

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2007 Jean-Yves Winum

, Marouan Rami, Andrea Scozzafava, Jean-Louis Montero, Claudiu Supuran

Carbonic anhydrase IX : a new druggable target for the design of antitumor agents

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2008 Jean-Yves Winum

, Stephen Kohler, Andrea Scozzafava, Jean-Louis Montero, Claudiu Supuran

Targeting bacterial metalloenzymes : a new strategy for the development of anti-infective agents.

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Marouan Rami, Jean-Yves Winum

, Alessio Innocenti, Jean-Louis Montero, Andrea Scozzafava, Claudiu T. Supuran

Carbonic anhydrase inhibitors. Copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor associated isoforms IX and XII.

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2007 Jean-Yves Winum

Carbonic anhydrase IX inhibitors: fluorescent sulfonamides as therapeutic and diagnostic agents: Supuran CT; Scozzafava A: WO2006137092

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Fatma-Zohra Smaine, Jean-Yves Winum

, Jean-Louis Montero, Zine Regainia, Daniela Vullo, Andrea Scozzafava, Claudiu T. Supuran

Carbonic anhydrase inhibitors: Selective inhibition of the extracellular, tumor-associated isoforms IX and XII over isozymes I and II with glycosyl-thioureido-sulfonamides

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Pascale Joseph, Marie-Rose Abdo, Rose-Anne Boigegrain, Jean-Louis Montero, Jean-Yves Winum

, Stephan Köhler

Targeting of the Brucella suis Virulence Factor Histidinol Dehydrogenase by Histidinol Analogues Results in Inhibition of Intramacrophagic Multiplication of the Pathogen

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Marie-Rose Abdo, Pascale Joseph, Rose-Anne Boigegrain, Jean-Pierre Liautard, Jean-Louis Montero, Stephan Köhler, Jean-Yves Winum

Brucella suis histidinol dehydrogenase: Synthesis and inhibition studies of a series of substituted benzylic ketones derived from histidine

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Mounir Nessaib, Mohamed Abdaoui, Abed el Ghani Djahoudi, Mekki Kadri, Jean-Yves Winum

Synthesis of Substituted N-aryl-N-Sulfamoyloxazolidin-2-ones with Potential Antibacterial Activity

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Claudia Temperini, Jean-Yves Winum

, Jean-Louis Montero, Andrea Scozzafava, Claudiu T. Supuran

Carbonic Anhydrase Inhibitors. The X-ray crystal structure of the adduct of N-hydroxysulfamide with isozyme II explains why this new zinc binding function is effective in the design of potent inhibitors

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Anna Di Fiore, Andrea Scozzafava, Jean-Yves Winum

, Jean-Louis Montero, Carlo Pedone, Claudiu T. Supuran, Giuseppina De Simone

Carbonic anhydrase inhibitors: Binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties

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Jean-Yves Winum

, Anne Thiry, Khaled El Cheikh, Khaled El Cheikh, Jean-Michel Dogne, Jean-Louis Montero, Daniela Vullo, Andrea Scozzafava, Bernard Masereel, Claudiu T. Supuran

Carbonic Anhydrase Inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX and XIV with sulfonamides incorporating fructopyranose-thioureido tails

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Jean-Yves Winum

, Andrea Scozzafava, Jean-Louis Montero, Claudiu Supuran

Metal binding functions in the design of carbonic anhydrase inhibitors

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2006 Jean-Yves Winum

, Claudia Temperini, Khaled El Cheikh, Alessio Innocenti, Daniela Vullo, Samuele Ciattini

, Jean-Louis Montero, Andrea Scozzafava, Claudiu T. Supuran

Carbonic Anhydrase Inhibitors: Clash with Ala65 as a Means for Designing Inhibitors with Low Affinity for the Ubiquitous Isozyme II, Exemplified by the Crystal Structure of the Topiramate Sulfamide Analogue †

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Giuseppina De Simone

, Rosa Maria Vitale, Anna Di Fiore, Carlo Pedone, Andrea Scozzafava, Jean-Louis Montero, Jean-Yves Winum

, Claudiu T. Supuran

Carbonic Anhydrase Inhibitors: Hypoxia-Activatable Sulfonamides Incorporating Disulfide Bonds that Target the Tumor-Associated Isoform IX †

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Papers authored by Jean-Yves Winum