Federico Falchi - Dissemin

Papers authored by Federico Falchi

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2012 Marco Radi, Federico Falchi

, Anna Garbelli, Alberta Samuele, Vincenzo Bernardo, Stefania Paolucci, Fausto Baldanti, Silvia Schenone, Fabrizio Manetti

, Giovanni Maga, Maurizio Botta

Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors

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2011 Valentina Corradi, Manuela Mancini, Maria Alessandra Santucci, Teresa Carlomagno, Domenico Sanfelice, Mattia Mori, Giulia Vignaroli, Federico Falchi

, Fabrizio Manetti

, Marco Radi, Maurizio Botta

Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: The 14-3-3σ case

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Federica Arioli, Stella Borrelli, Francesco Colombo, Federico Falchi

, Irene Filippi, Emmanuele Crespan, Antonella Naldini, Giusy Scalia, Alessandra Silvani

, Giovanni Maga, Fabio Carraro, Maurizio Botta, Daniele Passarella

N-[2-Methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a Scaffold for the Synthesis of Inhibitors of Bcr-Abl

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Giovanni Maga, Federico Falchi

, Marco Radi, Lorenzo Botta, Gianni Casaluce, Martina Bernardini, Hamid Irannejad, Fabrizio Manetti

, Anna Garbelli, Alberta Samuele, Samantha Zanoli, José A. Esté, Emmanuel Gonzalez, Elisa Zucca, Stefania Paolucci and 5 other authors

Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation

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Anna Garbelli, Marco Radi, Federico Falchi

, Sandra Beermann, Samantha Zanoli, Fabrizio Manetti

, Ursula Dietrich, Maurizio Botta, Giovanni Maga

Targeting the Human DEAD-Box Polypeptide 3 (DDX3) RNA Helicase as a Novel Strategy to Inhibit Viral Replication

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S. Schenone, C. Brullo, F. Musumeci

, Mariangela Biava, F. Falchi

, M. Botta

Fyn Kinase in Brain Diseases and Cancer: The Search for Inhibitors

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2010 Marco Radi, Emmanuele Crespan, Federico Falchi

, Vincenzo Bernardo, Samantha Zanoli, Fabrizio Manetti

, Silvia Schenone, Giovanni Maga, Maurizio Botta

Design and Synthesis of Thiadiazoles and Thiazoles Targeting the Bcr-Abl T315I Mutant: from Docking False Positives to ATP-Noncompetitive Inhibitors

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2009 Federico Falchi

, Fabrizio Manetti

, Fabio Carraro, Antonella Naldini, Giovanni Maga, Emmanuele Crespan, Silvia Schenone, Olga Bruno, Chiara Brullo, Maurizio Botta

3D QSAR Models Built on Structure-Based Alignments of Abl Tyrosine Kinase Inhibitors

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Elena Dreassi

, Alessandra Tania Zizzari, Federico Falchi

, Silvia Schenone, Annalisa Santucci

, Giovanni Maga, Maurizio Botta

Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data

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2008 Giovanni Maga, Federico Falchi

, Anna Garbelli, Amalia Belfiore, Myriam Witvrouw, Fabrizio Manetti

, Maurizio Botta

Pharmacophore Modeling and Molecular Docking Led to the Discovery of Inhibitors of Human Immunodeficiency Virus-1 Replication Targeting the Human Cellular Aspartic Acid-Glutamic Acid-Alanine-Aspartic Acid Box Polypeptide 3

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Fabrizio Manetti

, Federico Falchi

, Emmanuele Crespan, Silvia Schenone, Giovanni Maga, Maurizio Botta

N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds

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Marco Radi, Emmanuele Crespan, Giorgia Botta, Federico Falchi

, Giovanni Maga, Fabrizio Manetti

, Valentina Corradi, Manuela Mancini, Maria Alessandra Santucci, Silvia Schenone, Maurizio Botta

Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents

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Papers authored by Federico Falchi