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Oxford University Press (OUP), Bioinformatics, 3(25), p. 415-416

DOI: 10.1093/bioinformatics/btn647

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arrayQualityMetrics—a bioconductor package for quality assessment of microarray data

Journal article published in 2008 by Audrey Kauffmann, Robert Gentleman, Wolfgang Huber ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Summary:: The assessment of data quality is a major concern in microarray analysis. arrayQualityMetrics is a Bioconductor package that provides a report with diagnostic plots for one or two colour microarray data. The quality metrics assess reproducibility, identify apparent outlier arrays and compute measures of signal-to-noise ratio. The tool handles most current microarray technologies and is amenable to use in automated analysis pipelines or for automatic report generation, as well as for use by individuals. The diagnosis of quality remains, in principle, a context-dependent judgement, but our tool provides powerful, automated, objective and comprehensive instruments on which to base a decision.