Published in
Royal Society of Chemistry, Journal of Materials Chemistry B: Materials for biology and medicine, 32(5), p. 6546-6556, 2017
DOI: 10.1039/c7tb01052d
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Construction of giant glycosidase inhibitors from iminosugar-substituted fullerene macromonomers
Journal article published in 2017 by
Thi Minh Nguyet Trinh,
Michel Holler,
Jérémy P. Schneider,
M. Isabel García-Moreno 
,
José M. García Fernández ,
Anne Bodlenner,
Philippe Compain ,
Carmen Ortiz Mellet ,
Jean-François Nierengarten
,
José M. García Fernández ,
Anne Bodlenner,
Philippe Compain ,
Carmen Ortiz Mellet ,
Jean-François Nierengarten
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Abstract
A dramatic enhancement in the glycosidase multivalent inhibitory effect was observed while going from a dodecavalent iminosugar ball to the corresponding giant molecule with 120 peripheral subunits.