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Cold Spring Harbor Laboratory Press, Genome Research, 4(10), p. 547-548, 2000

DOI: 10.1101/gr.10.4.547

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Using GeneWise in the Drosophila Annotation Experiment

Journal article published in 2000 by Ewan Birney ORCID, Richard Durbin
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The GeneWise method for combining gene prediction and homology searches was applied to the 2.9-Mb region from Drosophila melanogaster. The results from the Genome Annotation Assessment Project (GASP) showed that GeneWise provided reasonably accurate gene predictions. Further investigation indicates that many of the incorrect gene predictions from GeneWise were due to transposons with valid protein-coding genes and the remaining cases are pseudogenes or possible annotation oversights.