Published in

Nature Research, Nature, 6822(409), p. 827-828, 2001

DOI: 10.1038/35057004

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Mining the draft human genome

Journal article published in 2001 by Alex Bateman ORCID, Ewan Birney ORCID, Michele E. Clamp, Tim J. Hubbard
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Now that the draft human genome sequence is available, everyone wants to be able to use it. However, we have perhaps become complacent about our ability to turn new genomes into lists of genes. The higher volume of data associated with a larger genome is accompanied by a much greater increase in complexity. We need to appreciate both the scale of the challenge of vertebrate genome analysis and the limitations of current gene prediction methods and understanding.