To improve the properties of paper sheets, microfibrillated cellulose (MFC) was isolated from bleached bagasse pulp pretreated with xylanase enzymes and returned to the pulp in varying amounts. The standard hand sheet paper-making method was used. The effect of adding different amounts of MFC on tensile strength (wet and dry), tear resistance, burst strength, opacity, and porosity of paper sheets was studied. Adding MFC to bagasse pulp improved wet and dry tensile strength, but tear resistance and burst strength decreased with increasing amounts of MFC. Also, adding MFC to bagasse pulp did not significantly affect opacity, slightly decreased porosity, and tightened the texture of the paper sheets as observed from scanning electron microscopy images. The strength properties of paper sheets made from bagasse and MFC were compared with those of paper sheets made from bagasse and softwood fibers. Paper sheets containing MFC had higher tensile strength (wet and dry) than those containing softwood fibers, but the later had higher tear resistance and burst strength.