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Royal Society of Chemistry, Soft Matter, 8(12), p. 2381-2391
DOI: 10.1039/c5sm02857d
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One-dimensional collective migration of a proliferating cell monolayer
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Abstract
Motivated by recent experiments on the expansion of highly cohesive cell sheets, our model of collective cell migration in one spatial dimension shows that constant front velocity results from the combined mechanical effects of bulk cell proliferation and front lamellipodial activity.