Evaluation of Renal Blood Flow in Chronic Kidney Disease Using Arterial Spin Labeling Perfusion Magnetic Resonance Imaging
Journal article published in 2017 by
Lu-Ping Li,
Huan Tan,
Jon M. Thacker,
Wei Li,
Ying Zhou,
Orly Kohn,
Stuart M. Sprague,
Pottumarthi V. Prasad
Abstract
Chronic kidney disease (CKD) is known to be associated with reduced renal blood flow. However, data in humans are limited to date. Methods: In this study, noninvasive arterial spin labeling magnetic resonance imaging data were acquired in 33 patients with diabetes and stage 3 CKD as well as in 30 healthy controls. Results: A significantly lower renal blood flow in both the cortex (108.4 ± 36.4 vs. 207.3 ± 41.8; P