Background: The relationship between age and 3D rotations objectivized with multisegment foot models has not been quantified until now. The purpose of this study was therefore to investigate the relationship between age and multi-segment foot kinematics in a cross-sectional database. Methods: Barefoot multi-segment foot kinematics of thirty two typically developing boys, aged 6–20 years, were captured with the Rizzoli Multi-segment Foot Model. One-dimensional statistical parametric mapping linear regression was used to examine the relationship between age and 3D inter-segment rotations of the dominant leg during the full gait cycle. Results: Age was significantly correlated with sagittal plane kinematics of the midfoot and the calcaneusmetatarsus inter-segment angle (p