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Royal Society of Chemistry, Nanoscale, 36(8), p. 16192-16196

DOI: 10.1039/c6nr03878f

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GAG mimetic functionalised solid and mesoporous silica nanoparticles as viral entry inhibitors of herpes simplex type 1 and type 2 viruses

Journal article published in 2016 by Edward C. Lee, Nicholas Davis-Poynter, Chau T. H. Nguyen, Amelia A. Peters, Gregory R. Monteith, Ekaterina Strounina, Amirali Popat, Benjamin Paul Ross ORCID
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

A glycosaminoglycan mimetic was attached to the surface of solid and mesoporous silica nanoparticles to create novel antiviral agents against herpes simplex type 1 and type 2 viruses. The nanoparticles act as viral entry inhibitors that appear to block viral attachment and penetration into susceptible cells.