We relate the case of a 17 year old girl with active pulmonary tuberculosis which mimicked a severe community-acquired pneumonia (CAP) associated to rhabdomyolysis. This report underlines the importance of excluding the diagnosis of pulmonary tuberculosis in any case of CAP which does not respond to standard antibiotic therapy, remembering that the empiric use of fluoroquinolones could delay the initiation of anti-tuberculosis treatment. This is, to our knowledge, the first description of a case of pulmonary tuberculosis complicated with rhabdomyolysis in a young girl without comorbidities.