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American Society for Cell Biology, Molecular Biology of the Cell, 22(22), p. 4220-4226

DOI: 10.1091/mbc.e11-02-0173

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Asymmetric cortical extension shifts cleavage furrow position in Drosophila neuroblasts

Journal article published in 2011 by Marisa Connell ORCID, Clemens Cabernard ORCID, Derek Ricketson, Chris Q. Doe, Kenneth E. Prehoda
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

A spindle-independent, myosin II–containing domain causes asymmetric cortical extension during anaphase of asymmetrically dividing Drosophila neuroblasts. Heterotrimeric G-proteins regulate the activity of the myosin II domain, and their loss leads to symmetric expansion and daughter cell size.