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Wiley, Angewandte Chemie International Edition, 49(53), p. 13573-13577, 2014

DOI: 10.1002/anie.201408355

Wiley, Angewandte Chemie, 49(126), p. 13791-13795, 2014

DOI: 10.1002/ange.201408355

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A general palladium-catalyzed method for alkylation of heteroarenes using secondary and tertiary alkyl halides

Journal article published in 2014 by Xiaojin Wu, Jessica Wei Ting See, Kai Xu, Hajime Hirao, Julien Roger, Jean-Cyrille Hierso ORCID, Jianrong Steve Zhou
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

A general alkylation of heterocycles using a simple palladium catalyst is reported. Most classes of heterocycles, including indoles and pyridines, efficiently coupled with unactivated secondary and tertiary alkyl halides. An alkyl radical addition to neutral heteroarenes is most likely involved.