Cholecystokinin-1 receptor antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anticancer agents - Eric Lattmann, Steven Russel, S. T. Russell, Carl H. Schwalbe, Andrew Shortt, P. N. Balaram, Eva Theochari, Muhanad Alharbi, Ramesh Narayanan, Pornthip Lattmann - Dissemin

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Royal Society of Chemistry, MedChemComm, 6(7), p. 1138-1145, 2016

DOI: 10.1039/c6md00052e

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Cholecystokinin-1 receptor antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anticancer agents

Journal article published in 2016 by Eric Lattmann, Steven Russel, S. T. Russell, Carl H. Schwalbe, Andrew Shortt, P. N. Balaram, Eva Theochari, Muhanad Alharbi, Ramesh Narayanan, Pornthip Lattmann

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Abstract

Hydroxy-pyrrolones, which were potent CCK1R antagonists, showed nanomolarin vitroactivity and anticancer activityin vivofor colon and pancreatic cancer.