Published in
American Society of Hematology, Blood, 26(125), p. 4052-4059, 2015
DOI: 10.1182/blood-2014-12-617282
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- American Society of Hematology | PDF
- [europepmc.org] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency
Journal article published in 2015 by
Mahadesh A. J. Prasad,
Jonas Ungerback,
Josefine Åhsberg,
J. Ahsberg,
Rajesh Somasundaram,
Tobias Strid,
Malin Larsson,
Robert Mansson 
,
Ayla De Paepe,
Henrik Lilljebjorn,
Thoas Fioretos,
James Hagman,
Mikael Sigvardsson
,
Ayla De Paepe,
Henrik Lilljebjorn,
Thoas Fioretos,
James Hagman,
Mikael Sigvardsson
This paper is made freely available by the publisher.
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Abstract
Key Points Ebf1 regulates DNA repair in a dose-dependent manner. Combined heterozygote loss of Ebf1 and Pax5 predisposes for leukemia development.