Published in
American Society of Hematology, Blood, 15(122), p. 2654-2663, 2013
DOI: 10.1182/blood-2013-02-484055
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Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma.
Journal article published in 2013 by
Stanley C. W. Lee 
,
Belinda Phipson,
Craig D. Hyland,
Huei San Leong,
Rhys S. Allan,
Aaron Lun,
Douglas J. Hilton,
Stephen L. Nutt ,
Marnie E. Blewitt,
Gordon K. Smyth,
Warren S. Alexander,
Ian J. Majewski
,
Belinda Phipson,
Craig D. Hyland,
Huei San Leong,
Rhys S. Allan,
Aaron Lun,
Douglas J. Hilton,
Stephen L. Nutt ,
Marnie E. Blewitt,
Gordon K. Smyth,
Warren S. Alexander,
Ian J. Majewski
This paper is made freely available by the publisher.
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Abstract
Key Points PRC1 and PRC2 have opposing activity in Eμ-myc lymphoma. Inhibition of PRC2 leads to increased self-renewal in B-cell progenitors.