Published in

American Society for Microbiology, Journal of Clinical Microbiology, 5(53), p. 1758-1760, 2015

DOI: 10.1128/jcm.00531-15

Links

Tools

Export citation

Search in Google Scholar

A Novel Technique for Detecting Antibiotic-Resistant Typhoid from Rapid Diagnostic Tests

Journal article published in 2015 by Caoimhe Nic Fhogartaigh, Caoimhe Nic Fhogartaigh, David A. B. Dance ORCID, Viengmon Davong, Pisey Tann, Rattanaphone Phetsouvanh, Paul Turner, Sabine Dittrich, Paul N. Newton
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Green circle
Postprint: archiving allowed
Upload
Orange circle
Published version: archiving restricted
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

ABSTRACT Fluoroquinolone-resistant typhoid is increasing. An antigen-detecting rapid diagnotic test (RDT) can rapidly diagnose typhoid from blood cultures. A simple, inexpensive molecular technique performed with DNA from positive RDTs accurately identified gyrA mutations consistent with phenotypic susceptibility testing results. Field diagnosis combined with centralized molecular resistance testing could improve typhoid management and surveillance in low-resource settings.