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Wiley, Angewandte Chemie International Edition, 17(51), p. 4128-4130, 2012

DOI: 10.1002/anie.201201001

Wiley, Angewandte Chemie, 17(124), p. 4204-4206, 2012

DOI: 10.1002/ange.201201001

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Asymmetric Total Synthesis of (+)-Merobatzelladine B

Journal article published in 2012 by Nicholas R. Babij, John P. Wolfe ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The first total synthesis of (+)-merobatzelladine B was accomplished using an iterative sequence of stereoselective Pd-catalyzed alkene carboamination reactions for formation of two of the three rings. This represents a new strategy for the generation of polycyclic guanidine natural products, and provides access to compounds with a syn-relationship between the C6 H-atom and the C8 alkyl group.