Published in
Elsevier, Arabian Journal of Chemistry, 6(8), p. 892-896, 2015
DOI: 10.1016/j.arabjc.2014.01.024
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Efficient and selective α-bromination of carbonyl compounds with N-bromosuccinimide under microwave
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Abstract
A highly efficient method for the synthesis of α-halocarbonyl compounds has been achieved via selective monobromination of aromatic and aliphatic carbonyl compounds with N-bromosuccinimide catalyzed by p-touenesulfonic acid under microwave irradiation within 30 minutes.