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Elsevier, Drug and Alcohol Dependence, (151), p. 236-240, 2015

DOI: 10.1016/j.drugalcdep.2015.03.035

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The association of rs1051730 genotype on adherence to and consumption of prescribed nicotine replacement therapy dose during a smoking cessation attempt

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

•We explore the impact of rs1051730 on nicotine replacement therapy (NRT) use in a smoking cessation trial.•Outcomes were NRT prescription adherence rate (%) and daily consumption (mg).•rs1051730 was associated with both outcomes at 7 days post quit attempt.•Each copy of the minor allele corresponded to a 1 mg decrease in daily NRT consumption.•No evidence of effect of genotype on either outcome observed at 28 days.