Springer (part of Springer Nature), Acta Mechanica Sinica, 6(28), p. 1545-1550
DOI: 10.1007/s10409-012-0165-9
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We present our theoretical analysis and coarsegrained molecular dynamics (CGMD) simulation results to describe the mechanics of breakup of spherical vesicles driven by changes in spontaneous curvature. Systematic CGMD simulations reveal the phase diagrams for the breakup and show richness in breakup morphologies. A theoretical model based on Griffith fracture mechanics is developed and used to predict the breakup condition.