Supplementary tables and figures. Table S1: number of individuals and their ethnicities from three different datasets used in the haplotype analyses: (a) England North West; (b) Allele Frequency Net Database (AFND); (c) dbMHC database. Table S2: Hardy-Weinberg proportions calculated for five loci: HLA-A, -B, -C, -DRB1 and -DQB1. Table S3: LD values estimated by the PyPop software using different statistics. Table S4: distribution of HLA alleles associated with drug-induced liver injury by: (a) major ethnic groups in the AFND; (b) geographic region in the AFND; and (c) geographic region in dbMHC. Table S5: list of alleles for each allele with suffix 'g'. Table S6: counts (frequencies) of Caucasian individuals from the ENW archive (n = 298) who carry alleles and two loci haplotypes implicated in DILI. Figure S1: alleles associated with DILI selected from the AFND and their frequencies.