Sociedade Brasileira de Cirurgia Cardiovascular, Revista Brasileira de Cirurgia Cardiovascular
DOI: 10.5935/1678-9741.20150045
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Objective: This study aimed to show the effects of intra-operative diltiazem infusion on flow in arteriel and venous grafts in coronary artery bypass graft surgery. Patients and Methods: 140 patients with a total of 361 grafts [205 (57%) arterial and 156 (43%) venous] underwent isolated coronary surgery. All the grafts were measured by intraoperative transit time flow meter intra-operatively. Group A (n=70) consisting of patients who received diltiazem infusion (dose of 2.5 microgram/kg/min), and Group B (n=70) who didn't receive diltiazem infusion. Results: Mean graft flow values of left internal mammary artery were 53 ml/min in Group A and 40 ml/min in Group B (P < 0.001). Pulsatility index (PI) values of left internal mammary artery for Group A and Group B were 2.6 and 3.0 respectively (P < 0.001). No statistically significant difference was found between venous graft parameters. Conclusion: We suggest an effect of diltiazem infusion in preventing early vasospasm and in increasing graft flows in coronary artery bypass graft operations.