As paleoceanographic archives, deep sea coral skeletons offer the potential for high temporal resolution and precise absolute dating, but have not been fully investigated for geochemical reconstructions of past ocean conditions. Here we assess the utility of skeletal P/Ca, Ba/Ca and U/Ca in the deep sea coral D. dianthus as proxies of dissolved phosphate (remineralized at shallow depths), dissolved barium (trace element with silicate-type distribution) and carbonate ion concentrations, respectively. Mea-surements of these proxies in globally distributed D. dianthus specimens show clear dependence on corresponding seawater prop-erties. Linear regression fits of mean coral Element/Ca ratios against seawater properties yield the equations: P/Ca coral (lmol/ mol) = (0.6 ± 0.1) P/Ca sw (lmol/mol) – (23 ± 18), R 2 = 0.6, n = 16 and Ba/Ca coral (lmol/mol) = (1.4 ± 0.3) Ba/Ca sw (lmol/ mol) + (0 ± 2), R 2 = 0.6, n = 17; no significant relationship is observed between the residuals of each regression and seawater temperature, salinity, pressure, pH or carbonate ion concentrations, suggesting that these variables were not significant second-ary dependencies of these proxies. Four D. dianthus specimens growing at locations with O arag 6 0.6 displayed markedly depleted P/Ca compared to the regression based on the remaining samples, a behavior attributed to an undersaturation effect. These corals were excluded from the calibration. Coral U/Ca correlates with seawater carbonate ion: U/Ca coral (lmol/ mol) = (À0.016 ± 0.003) ½CO 2À 3 Š (lmol/kg) + (3.2 ± 0.3), R 2 = 0.6, n = 17. The residuals of the U/Ca calibration are not signif-icantly related to temperature, salinity, or pressure. Scatter about the linear calibration lines is attributed to imperfect spatial-temporal matches between the selected globally distributed specimens and available water column chemical data, and potentially to unresolved additional effects. The uncertainties of these initial proxy calibration regressions predict that dissolved phosphate could be reconstructed to ±0.4 lmol/kg (for 1.3–1.9 lmol/kg phosphate), and dissolved Ba to ±19 nmol/kg (for 41–82 nmol/ kg Ba sw). Carbonate ion concentration derived from U/Ca has an uncertainty of ±31lmol/kg (for 60–120 lmol=kg CO 2À 3). The effect of microskeletal variability on P/Ca, Ba/Ca, and U/Ca was also assessed, with emphasis on centers of calcification, Fe–Mn phases, and external contaminants. Overall, the results show strong potential for reconstructing aspects of water mass mixing and biogeochemical processes in intermediate and deep waters using fossil deep-sea corals.