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American Heart Association, Arteriosclerosis, Thrombosis, and Vascular Biology, 2(28), p. 353-359, 2008

DOI: 10.1161/atvbaha.107.151928

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Tea Consumption Is Inversely Associated With Carotid Plaques in Women

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Objective— The aim of this study was to assess the relationship of tea consumption with common carotid artery intima-media thickness (CCA-IMT) and carotid plaques. Methods and Results— The study was performed on 6597 subjects aged ≥65 years, recruited in the French population for the Three-City Study. Atherosclerotic plaques in the extracranial carotid arteries and CCA-IMT were measured using a standardized protocol. Results were tested for replication in another, younger, French population sample (EVA-Study, 1123 subjects). In the Three-City Study, increasing daily tea consumption was associated with a lower prevalence of carotid plaques in women: 44.0%, 42.5%, and 33.7% in women drinking no tea, 1 to 2 cups/d, and ≥3 cups/d ( P =0.0001). This association was independent of age, center, major vascular risk factors, educational level, and dietary habits (adjOR=0.68[95%CI:0.54 to 0.86] for women drinking ≥3 cups/d compared with none). There was no association of tea consumption with carotid plaques in men, or CCA-IMT in both genders. In the EVA-Study, carotid plaque frequency was 18.8%, 18.5%, and 8.9% in women drinking no tea, 1 to 2 cups/d, and ≥3 cups/d ( P =0.08). Conclusion— In a large sample of elderly community subjects we showed for the first time that carotid plaques were less frequent with increasing tea consumption in women.