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Cell Press, Current Biology, 14(12), p. R479-R481, 2002

DOI: 10.1016/s0960-9822(02)00962-4

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Cell Polarity: Posterior Par-1 Prevents Proteolysis

Journal article published in 2002 by Richard Benton, Daniel St Johnston ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

The Par-1 kinase is required for anterior-posterior axis formation in Drosophila. New work has identified the posterior determinant, Oskar, as a Par-1 substrate. Phosphorylation stabilises Oskar, revealing a novel mechanism controlling its asymmetric distribution.