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Oxford University Press (OUP), Bioinformatics, 14(30), p. 2009-2017

DOI: 10.1093/bioinformatics/btu156

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Basin Hopping Graph: a computational framework to characterize RNA folding landscapes

Journal article published in 2014 by Marcel Kucharík, Ivo L. Hofacker, Peter F. Stadler ORCID, Jing Qin
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Motivation: RNA folding is a complicated kinetic process. The minimum free energy structure provides only a static view of the most stable conformational state of the system. It is insufficient to give detailed insights into the dynamic behavior of RNAs. A sufficiently sophisticated analysis of the folding free energy landscape, however, can provide the relevant information.