We completed a meta-analysis of regional and global climate model simulations (n=96) of the impact of Amazonian deforestation on Amazon basin rainfall. Across all simulations, mean (±1σ) change in annual mean Amazon basin rainfall was -12±11%. Variability in simulated rainfall was not explained by differences in model resolution or surface parameters. Across all simulations we find a negative linear relationship between rainfall and deforestation extent, although individual studies often simulate a nonlinear response. Using the linear relationship, we estimate that deforestation in 2010 has reduced annual mean rainfall across the Amazon basin by 1.8±0.3%, less than the interannual variability in observed rainfall. This may explain why a reduction in Amazon rainfall has not consistently been observed. We estimate that business-as-usual deforestation (based on deforestation rates prior to 2004) would lead to an 8.1±1.4% reduction in annual mean Amazon basin rainfall by 2050, greater than natural variability.