Published in
American Thoracic Society, American Journal of Respiratory and Critical Care Medicine, 4(185), p. 373-381, 2012
DOI: 10.1164/rccm.201108-1382oc
Links
- American Thoracic Society
- [www.ncbi.nlm.nih.gov] | PDF
- [www.researchgate.net] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
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Variable DNA Methylation Is Associated with Chronic Obstructive Pulmonary Disease and Lung Function
Journal article published in 2012 by
Weiliang Qiu,
Andrea Baccarelli,
Vincent J. Carey,
Nadia Boutaoui,
Helene Bacherman,
Barbara Klanderman,
Stephen Rennard,
Alvar Agusti,
Wayne Anderson,
David A. Lomas,
Dawn L. DeMeo
This paper is available in a repository.
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Abstract
Rationale: Chronic obstructive pulmonary disease (COPD) is associated with local (lung) and systemic (blood) inflammation and manifestations. DNA methylation is an important regulator of gene transcription, and global and specific gene methylation marks may vary with cigarette smoke exposure.